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Genetics

2020-8-25
RNA quality control system goes awry in frontotemporal lobar degeneration

Researchers from Osaka University have uncovered that the RNA exosome is critical for the degradation of defective repeat RNA derived from C9orf72 rep...

2020-8-1
Change isn’t a good thing for Japanese rheumatoid arthritis patients

Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA) that dramatically increases the risk of death. In a recent study...

2020-6-23
The protein that stands between us and autoimmunity

Researchers from Osaka University identified the epigenetic proteins Tet2 and Tet3 as key regulators of B cell function. They showed that these protei...

2020-5-27
A natural amino acid could be a novel treatment for polyglutamine diseases

Researchers from Osaka University, National Center of Neurology and Psychiatry, and Niigata University identified the amino acid arginine as a potenti...

2020-2-20
A tadpole with a twist: Left–right asymmetric development of Oikopleura dioica

2020-2-15
Huntington’s disease-causing DNA repeat mutations reversed in the lab

An international team of researchers identifies a compound that corrects genetic abnormalities involved in the onset and progression of Huntington’s d...

2019-11-19
Researchers split the “AtoM” in search of a treatment for rheumatoid arthritis

Rheumatoid arthritis is a chronic, disabling disease in which the joints become swollen and painfully inflamed. Current treatments can only reduce sym...

2019-11-8
When your microbiome and your genome aren’t a good combination

Research carried out by a team led by Osaka University has shown that various Prevotella species, along with several specific genes and biological pat...

2019-10-17
Keep quiet or be eliminated: how cell competition modulates morphogen gradients

Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allow...

2019-9-13
Multidrug resistance: Not as recent as we thought

Researchers from Osaka University found that the ancient RND-type multidrug efflux pump AcrB from Haemophilus influenzae targets the same drugs as its...

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