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2017-11-7

New Strategy for Multiple Myeloma Immunotherapy

Osaka University study unveils new target for monoclonal antibody-based treatment of cancer

Cancer-specific proteins have been identified for the development of monoclonal antibody (mA)-based therapies, but there remains a need to uncover new...

2017-9-15

Novel Small Antibody Fragment: A Valuable Tool in Crystallography

Osaka University researchers create new chimeric antibody fragment to aid structural determination of “uncrystallizable” target protein

Achieving quality diffracting crystals remains the major bottleneck in macromolecular x-ray crystallography. Antibody fragments have been used to aid ...

2017-9-12

Epigenetic gene expression mechanism in light sensitive cells in the eye identified

Mechanism for establishing retinal photoreceptor cell identity discovered

A group of researchers clarified the epigenetic control system in retinal photoreceptor cells, demonstrating its importance in neural development. Thi...

2017-9-2

Proteins keep a grip on cells

Japanese scientists at Osaka University have revealed new structural information on the integrin-laminin interaction

Japanese scientists at Osaka University have revealed new structural information on the integrin-laminin interaction. These findings provide important...

2017-8-22

A new genetic marker for schizophrenia

Japanese scientists find a rare genetic variant that shows strong association with schizophrenia

2017-8-1

Using DNA to predict schizophrenia and autism

Osaka University researchers show in a multi-institute collaboration that a single amino acid substitution in the protein CX3CR1 may act as predictor for schizophrenia and autism

2017-6-22

Detailed Structure of the Sweat Gland Revealed

Researchers at Osaka University have characterized the structure of human sweat glands down to the single cell level; the findings clarify the functional components of these glands and their interactions with the vasculature and nervous system, and thus could lead to treatments for sweating disorders

Osaka University researchers applied the technique of whole-mount immunostaining to characterize the structural features of human sweat glands as well...

2017-5-23

A fish of all flavours

Japanese researchers achieve atomic resolution images of taste receptors in fish

Japanese researchers achieve atomic resolution images of taste receptors in fish. The structure explains why so few receptors are sufficient to sense ...

2017-4-11

Successful synthesis of a new insulin analogue Selenoinsulin

Will lead to the development of long-lasting insulin preparations

A group of researchers succeeded in developing synthetic insulin analogues selenoinsulin (Se-Ins) through the replacement of the interchain disulfide...

2017-4-10

Discovery of low noise, low viscosity, and low cost carrier of proteins for serial crystallography (SFX)

A joint group of researchers discovered that it was possible to achieve a stable supply of crystals and reduction of background scattering noise at lo...

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