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Life Sciences & Medicine

CD4 T Cells, Xenobiotic Transporters, and Metabolites in Inflammatory Bowel Diseases

International researchers show CD4+ T effector cells express xenobiotic transporter Mdr1 in the presence of bile acids to maintain homeostasis in the small intestine

Few studies have investigated the interaction between intestinal T cells with metabolites. Researchers have now shown in mice CD4+ T effector (Teff) c...

Life Sciences & Medicine

Phase III clinical trials for stem cell-based cartilage regeneration therapy have started

Life Sciences & Medicine

Next-generation vascular endoscopic catheter with head-mounted image sensor developed through Osaka University-Panasonic Collaboration

A group for researchers has succeeded in the commercialization of a vascular endoscopic catheter with a head-mounted image sensor. This vascular endos...

Life Sciences & Medicine

Immune diseases inflict identical twins differently

Osaka University scientists explain why only one identical twin is at risk for autoimmune diseases

Life Sciences & Medicine

New Strategy for Multiple Myeloma Immunotherapy

Osaka University study unveils new target for monoclonal antibody-based treatment of cancer

Cancer-specific proteins have been identified for the development of monoclonal antibody (mA)-based therapies, but there remains a need to uncover new...

Life Sciences & Medicine

Pathological Mechanisms in Congenital Myotonic Dystrophy Unveiled

Osaka University-centered researchers reveal abnormal myokine signaling in congenital myotonic dystrophy

Congenital myotonic dystrophy (CDM) is a severe form of myotonic dystrophy characterized by muscle fiber immaturity not observed in adult DM, suggesti...

Life Sciences & Medicine

Successful implantation of heart pump with power cable behind the ear, a Japan first!

Life Sciences & Medicine

Mending hearts in three dimensions

Kyoto-Osaka team uses hiPSCs to repair myocardial infarctions in rats

Life Sciences & Medicine

Successful cardiogenic shock treatment using a percutaneous left ventricular assist device


New mutations in iPS cells are mainly concentrated in non-transcriptional regions


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