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2016-11-2

Efficient induction of vascular endothelial cells from human pluripotential stem cells (hPSCs) using extracellular matrix (ECM)s

A joint group of researchers succeeded in developing a method for efficient differentiation of functional vascular endothelial cells (ECs) from hPSCs ...

2016-11-2

Peptide for inhibiting the function pf protein that may cause cancer infiltration and osteoporosis created

Will become an active region in designing new drugs

A group of researchers succeeded in obtaining plexin B1 (PlxnB1)-binding macrocyclic peptide, PB1m6. PlxnB1 is a semaphorin 4D (Sema4D) receptor, and ...

2016-9-9

Successful development of specific antibodies to hepatocyte growth factor (HGF)

A step towards the clarification of molecular mechanism for HGF signaling

A group of researchers succeeded in creating monoclonal antibodies against Hepatocyte growth factor (HGF), which is deeply related to treatment of amy...

2016-6-14

Calredoxin, a novel protein for promoting efficient photosynthesis

A key player behind the reduction of oxidative stress in photosynthetic organisms

A group of researchers reported on the structure and function of a novel protein named “Calredoxin.” Calredoxin binds calcium and catalyzes in depende...

2016-4-18

Medium for delivering protein crystals with low damage discovered

A step toward the development of new drugs through crystal structure analysis of proteins

A joint group of researchers found that hyaluronic acid could be used as a medium for delivering protein crystals in Serial Femtosecond Crystallograph...

2016-4-4

The discovery of a totally new kind of “mark” in human cell nucleus

Will lead to the clarification of mechanism of development of metabolism and cardiovascular disorder

A group of researchers verified the presence of Histone H4 lysine 20 acetylation (H4K20ac) by using mass spectrometry. H4K20ac is a mark of the cell n...

2016-3-19

Repair full of mistakes may develop cancer!?

Molecular mechanism of repair of DNA damaged by radiation clarified

A group of researchers found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain...

2016-3-14

Developing New Therapeutics For Parkinson's Disease

Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults

A group of researchers presented data which reveals that necdin promotes mitochondrial biogenesis through stabilization of endogenous PGC-1α to exert ...

2016-2-25

Successful 1,000-fold enhancement of reaction velocity constants for proteins’ change into toxic substances

Will apply to early diagnosis, treatment, and risks associated with ultrasonic irradiation regarding Alzheimer’s disease

A group of researchers succeeded in increasing the velocity constant for a reaction in which proteins causing Alzheimer disease (AD) turn into toxic s...

2016-2-19

Mass-production of proteins necessary for maintenance and proliferation of stem cells, the key to regenerative medicine, established

A new method for safe mass-production with no impurities

A group of researchers developed a new method for purifying and storing Wnts. This group’s achievement has enabled the preparation of Wnts in large a...

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