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Molecular Biology

2019-3-20
Electron Accelerators Reveal the Radical Secrets of Antioxidants

An Osaka University professor has demonstrated for the first time the value of linear particle accelerators for the generation of free radicals inside...

2019-3-11
Winning the Arms Race: Analysis Reveals Key Gene for Bacterial Infection

Researchers at Osaka University applied molecular evolutionary analysis to quantify the severity of negative selection pressures on genes encoding the...

2019-3-6
Hematopoietic Stem Cells: Making Blood Thicker than Water

An Osaka University-led team revealed that Ragnase-1 is a key regulator of the self-renewal and differentiation of hematopoietic stem and progenitor c...

2019-2-26
Gut Instinct: Bile Acid-Triggered Bacterial Adaptation Characterized

An international team led by Osaka University researchers has shown how the Salmonella protein RamR senses bile acids present in the gut, leading to t...

2019-2-22
Treatment to a T? Taking a BiTE Out of Lung Cancer

An Osaka University-led research team assayed T cell cytotoxicity in tumor tissue in lung cancer, along with normal lung tissue and peripheral blood. ...

2019-2-6
More Physical Than Chemical: Researchers Show What Really Gets Cells Going

Collective cell migration is essential in many organisms, with roles in human cellular processes including cancer invasion and wound healing. Now, a t...

2019-2-5
Large-scale Study Reveals Genetic Risk of Diabetes in the Japanese Population

Researchers at Osaka University, The University of Tokyo, RIKEN, and others performed a meta-analysis using data on over 36,000 Japanese sufferers of ...

2019-1-29
Big Data Provides Clues for Characterizing Immunity in Japanese

Osaka University researchers used various sets of large-scale data to characterize the variation and phenotypic associations of an immunity-related ge...

2019-1-24
Small Metabolites Have Big Effects on the Intestinal Immune Response

Normal gut bacteria are instrumental in inducing an immune response in the presence of invading pathogens. However, exactly how commensal bacteria cau...

2019-1-15
Therapeutic and Diagnostic Functions of One Antibody for Pancreatic Cancer

Osaka University researchers developed monoclonal antibodies against CKAP4—a plasma membrane protein—and found that it was released from pancreatic ca...

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