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Immunology/Allergies/Asthma

2019-2-7
When Good Cells Go Bad: Regulating the MS-Causing Properties of Th17 Cells

Multiple sclerosis (MS) and other inflammatory autoimmune diseases are characterized by localized inflammation in various tissues, including the brain...

2019-1-24
Small Metabolites Have Big Effects on the Intestinal Immune Response

Normal gut bacteria are instrumental in inducing an immune response in the presence of invading pathogens. However, exactly how commensal bacteria cau...

2019-1-11
Resist! TAK1 enables endothelial cells to avoid apoptosis

TNFα-induced cell death is tightly regulated and resisted in endothelial cells. Here, an Osaka University-led research team used a unique type of mous...

2018-11-21
How low can we go? Nanopore detection of single flu viruses to control outbreaks

Influenza is a highly contagious respiratory disease that may cause a serious outbreak at any time. Here, an Osaka University-led research team develo...

2018-11-20
Going viral: New cells for norovirus production in the lab

Human norovirus is a major cause of infections that can be particularly dangerous to children and elderly people. Here, an Osaka University-led resear...

2018-11-20
Lung Neuropeptide Exacerbates Lethal Influenza Virus Infection

Researchers found that lung immune cells (phagocytes) produce increased levels of neuropeptide Y (NPY) when mice are infected with severe influenza vi...

2018-11-19
Getting things under control: new mouse model aids study of immunomodulation

Mice are resistant to immunomodulatory drugs (IMiDs). As a result, studying the effects of IMiDs was not possible in existing types of mice. Here, an ...

2018-10-23
The Mincle receptor provides protective immunity against Group A Streptococcus

Group A Streptococcus (GAS) causes invasive infections that result in high mortality. Despite being susceptible to many antibiotics, GAS continues to ...

2018-8-29
Dectin-1-mediated pain is critical for the resolution of fungal inflammation

Candidiasis is a painful infection that affects a large number of individuals, occasionally causing severe pain that is solely controlled by resolutio...

2017-4-18
Breakdown of Neutrophil Protein Causes Severe Autoimmune Disease of Blood Vessels

Osaka University researchers revealed that patients with a severe autoimmune disease that attacks the blood vessels lack the membrane form of a protei...

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