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Helpful B cells lend a hand to developing neurons

Neuron myelination is critical to early mental development, and defects in myelination have been linked to neurodevelopmental disorders. Researchers a...

Efficacy of antibody targeting Devic’s disease proven in new animal model

Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG). A cure for NMO remains elusive. Osaka University r...

CD4 T Cells, Xenobiotic Transporters, and Metabolites in Inflammatory Bowel Diseases

Few studies have investigated the interaction between intestinal T cells with metabolites. Researchers have now shown in mice CD4+ T effector (Teff) c...

Discovery of key molecules involved in severe malaria

New Strategy for Multiple Myeloma Immunotherapy

Cancer-specific proteins have been identified for the development of monoclonal antibody (mA)-based therapies, but there remains a need to uncover new...

Novel Small Antibody Fragment: A Valuable Tool in Crystallography

Achieving quality diffracting crystals remains the major bottleneck in macromolecular x-ray crystallography. Antibody fragments have been used to aid ...

A lipid makes lymphocytes move swiftly within lymph nodes

A group at Osaka University has found for the first time that a lipid called lysophosphatidic acid (LPA) plays a vital role in regulating lymphocyte m...

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