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Immunology

2018-7-6
Step-by-Step Account of Systemic Lupus Erythematosus Development Revealed

Osaka University researchers elucidated the pathophysiology of systemic lupus erythematosus (SLE), an autoimmune disorder that causes inflammation and...

2018-5-23
Igniting the Rheumatoid Arthritis Flame Through A Cellular Cascade

Osaka University-led international researchers identified a network of cells responsible for secretion of a key inflammatory cytokine in development o...

2018-5-19
Neuron guidance factor found to play a key role in immune cell function

Macrophages are white blood cells that perform different functions with different energy needs. M2-type macrophages have anti-inflammatory properties ...

2018-4-18
Accepted or Rejected? Uncovering How Fate of B Cell is Determined

Osaka University-centered researchers identify the plasma cell-prone B cells in the light zone of germinal centers. Higher expression of the proteins ...

2018-3-6
Helpful B cells lend a hand to developing neurons

Neuron myelination is critical to early mental development, and defects in myelination have been linked to neurodevelopmental disorders. Researchers a...

2018-1-9
Efficacy of antibody targeting Devic’s disease proven in new animal model

Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG). A cure for NMO remains elusive. Osaka University r...

2017-12-20
CD4 T Cells, Xenobiotic Transporters, and Metabolites in Inflammatory Bowel Diseases

Few studies have investigated the interaction between intestinal T cells with metabolites. Researchers have now shown in mice CD4+ T effector (Teff) c...

2017-11-30
Discovery of key molecules involved in severe malaria

2017-11-7
New Strategy for Multiple Myeloma Immunotherapy

Cancer-specific proteins have been identified for the development of monoclonal antibody (mA)-based therapies, but there remains a need to uncover new...

2017-9-15
Novel Small Antibody Fragment: A Valuable Tool in Crystallography

Achieving quality diffracting crystals remains the major bottleneck in macromolecular x-ray crystallography. Antibody fragments have been used to aid ...

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