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Cell Biology

2020-9-29
Lipids, lysosomes, and autophagy: the keys to preventing kidney injury

Lysosomes are cellular waste disposal organelles containing potent enzymes that cause cellular damage if they leak out of ruptured lysosomes. In a rec...

2020-8-28
Faulty transportation of messenger RNA is the culprit in ALS

A team including Osaka University researchers has discovered a function for the protein missing in many types of ALS and FTLD, two neurodegenerative d...

2020-8-20
Is turning back the clock in aging fat cells a remedy for lifestyle diseases?

Researchers from Osaka University found that lifestyle diseases such as diabetes, high cholesterol, and fatty liver are caused by age-related changes ...

2020-7-11
Fat cell hormone boosts potential of stem cell therapy

Mesenchymal stem cell (MSC) therapy has shown promising results in the treatment of conditions ranging from liver cirrhosis to retinal damage, but res...

2020-6-23
The protein that stands between us and autoimmunity

Researchers from Osaka University identified the epigenetic proteins Tet2 and Tet3 as key regulators of B cell function. They showed that these protei...

2020-6-18
Antioxidant agent may prevent chronic kidney disease and Parkinson’s disease

Researchers from Osaka University developed a novel dietary silicon-based antioxidant agent with renoprotective and neuroprotective effects. They show...

2020-5-27
A natural amino acid could be a novel treatment for polyglutamine diseases

Researchers from Osaka University, National Center of Neurology and Psychiatry, and Niigata University identified the amino acid arginine as a potenti...

2020-5-22
A vaccine targeting aged cells mitigates metabolic disorders in obese mice

Researchers from Osaka University developed a novel vaccine that removes senescent T cells from adipose tissues. They showed that vaccinated obese mic...

2020-3-24
Modeling the human eye in a dish

Researchers from Osaka University developed and validated a novel PITX2-eGFP hiPSC reporter line to model the development of periocular mesenchymal ce...

2020-3-18
How tissues harm themselves during wound healing

Researchers from Osaka University discovered that increased expression of Rbm7 in apoptotic tissue cells results in the recruitment of segregated-nucl...

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