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Cell Biology

2019-6-7
Nuclear pore complex outer rings: no longer “one size fits all”

In eukaryotic cells, molecules can only move into or out of the nucleus through specialized channels called nuclear pore complexes (NPCs). Each NPC ha...

2019-5-21
Phosphorylation of Regnase-1 Lets IL-17 Run Amok

A research team led by Osaka University found that the cytokine interleukin (IL)-17 triggers the phosphorylation of mRNA-degrading enzyme Regnase-1, r...

2019-4-18
Location is everything for plant cell differentiation

During development, plant cell differentiation is guided by location rather than lineage. Now, researchers from Osaka University have shown that the a...

2019-3-6
Hematopoietic Stem Cells: Making Blood Thicker than Water

An Osaka University-led team revealed that Ragnase-1 is a key regulator of the self-renewal and differentiation of hematopoietic stem and progenitor c...

2019-2-22
Treatment to a T? Taking a BiTE Out of Lung Cancer

An Osaka University-led research team assayed T cell cytotoxicity in tumor tissue in lung cancer, along with normal lung tissue and peripheral blood. ...

2019-2-19
The key to increased lifespan? Rubicon alters autophagy in animals during aging

Autophagy is an important biological recycling mechanism that influences the progression of aging in animals. Here, age-related changes in autophagy w...

2019-2-6
More Physical Than Chemical: Researchers Show What Really Gets Cells Going

Collective cell migration is essential in many organisms, with roles in human cellular processes including cancer invasion and wound healing. Now, a t...

2019-1-24
Small Metabolites Have Big Effects on the Intestinal Immune Response

Normal gut bacteria are instrumental in inducing an immune response in the presence of invading pathogens. However, exactly how commensal bacteria cau...

2019-1-11
Resist! TAK1 enables endothelial cells to avoid apoptosis

TNFα-induced cell death is tightly regulated and resisted in endothelial cells. Here, an Osaka University-led research team used a unique type of mous...

2019-1-11
Keeping Chromosomes in Check: A New Role for Heterochromatin

Large changes in the structure of chromosomes are usually fatal for the cell or can lead to genetic diseases such as cancer. Many large chromosomal re...

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