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Life Sciences & Medicine
2019-10-17

Keep quiet or be eliminated: how cell competition modulates morphogen gradients

Osaka University-led study shows that communication between cells with normal and abnormal Wnt/β-catenin activity causes abnormal cells to die through production of reactive oxygen species

Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allow...

Life Sciences & Medicine
2019-9-24

No defects found in reproductive ability of male mice returning from short stay in space

Male mice raised in space using specially developed cages were returned safely to Earth. The sperm production/fertilizing ability of the mice were nor...

Life Sciences & Medicine
2019-8-30

Methylation of microRNA may be a new powerful biomarker for cancer

Researchers from Osaka University find a new way to distinguish individuals with early pancreatic cancer from healthy controls, representing a promising new metric in cancer diagnosis

Researchers from Osaka University found that levels of methylated microRNA were significantly higher in tissue and serum from cancer patients compared...

Life Sciences & Medicine
2019-8-27

Family genes that regulate sperm’s fertilizing ability discovered via genome editing technology

Life Sciences & Medicine
2019-7-17

New Method Increases Accuracy of Nontuberculous Mycobacteria Identification

Researchers from Osaka University and the University of the Ryukyus develop new software that can accurately identify nontuberculous mycobacteria, allowing faster implementation of targeted therapies

The more than 200 species of nontuberculous mycobacteria (NTM) are notoriously difficult to differentiate, delaying the implementation of targeted ant...

Life Sciences & Medicine
2019-6-12

Host factors that trigger differentiation of malaria Plasmodium clarified

Existing drugs could prevent malaria

Life Sciences & Medicine
2019-5-21

Phosphorylation of Regnase-1 Lets IL-17 Run Amok

A research team led by Osaka University finds that blocking the phosphorylation of mRNA-degrading enzyme Regnase-1 helps prevent excessive inflammation caused by unruly cytokine IL-17

A research team led by Osaka University found that the cytokine interleukin (IL)-17 triggers the phosphorylation of mRNA-degrading enzyme Regnase-1, r...

Life Sciences & Medicine
2019-5-14

COMMD3/8 protein complex: a potential drug target for treating inflammatory diseases

Researchers discover a molecule involved in immune cell migration that plays a critical role in establishing immune responses

Life Sciences & Medicine
2019-3-6

Hematopoietic Stem Cells: Making Blood Thicker than Water

Researchers at Osaka University reveal how a regulatory molecule ensures an appropriate supply of blood cells while avoiding the excessive proliferation associated with conditions like leukemia

An Osaka University-led team revealed that Ragnase-1 is a key regulator of the self-renewal and differentiation of hematopoietic stem and progenitor c...

2019-2-21

Probes for visualizing serine-metabolizing enzyme developed

Will help discover drug candidate compounds for malaria and cancer in screening

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