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Life Sciences & Medicine
2019-2-5

Large-scale Study Reveals Genetic Risk of Diabetes in the Japanese Population

Researchers have combined data from genetic studies and revealed 28 new genomic regions associated with type 2 diabetes, some variants of which are not found in other ethnic groups

Researchers at Osaka University, The University of Tokyo, RIKEN, and others performed a meta-analysis using data on over 36,000 Japanese sufferers of ...

Life Sciences & Medicine
2019-2-4

Japanese Study Finds Concerning Trends in Cervical Cancer and Treatment Response

Osaka University-centered study examines large-scale population survey and identifies increase in cervical cancer rate, along with younger patients’ surprising resistance to radiation therapy

Osaka University-centered research examined a large-scale Japanese data cohort for trends in cervical cancer prevalence, treatment, and survival. They...

Life Sciences & Medicine
2019-1-29

Big Data Provides Clues for Characterizing Immunity in Japanese

An Osaka University-centered research team has performed fine-mapping of the key immunity-related part of the genome, revealing associations between gene variants and over 50 different phenotypes in the Japanese

Osaka University researchers used various sets of large-scale data to characterize the variation and phenotypic associations of an immunity-related ge...

Life Sciences & Medicine
2019-1-24

Small Metabolites Have Big Effects on the Intestinal Immune Response

Researchers at Osaka University find that common bacterial metabolites pyruvate and lactate enhance the intestinal immune response and guard against infection by important gut pathogens

Normal gut bacteria are instrumental in inducing an immune response in the presence of invading pathogens. However, exactly how commensal bacteria cau...

Life Sciences & Medicine
2019-1-15

Therapeutic and Diagnostic Functions of One Antibody for Pancreatic Cancer

Osaka University researchers base biomarker detection and targeted therapy on the same protein from pancreatic cancer patients

Osaka University researchers developed monoclonal antibodies against CKAP4—a plasma membrane protein—and found that it was released from pancreatic ca...

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