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Life Sciences & Medicine
2019-12-11

Hematopoietic stem cell marker: A key player in the ontogeny of hematopoiesis

A research team led by Osaka University revealed that Endothelial cell-selective adhesion molecule, a surface marker for hematopoietic stem cells and ...

Life Sciences & Medicine
2019-12-6

Genomic cut and paste using a Class 1 CRISPR system

Japanese researchers led by Osaka University show that a Class 1 CRISPR gene editing system can achieve functional DNA repairs in human cells with no prominent off-target effects

Repairing faulty genes to prevent and cure disease is something researchers have been working towards for many years. While Class 2 CRISPR systems sho...

Life Sciences & Medicine
2019-11-29

Protein defect leaves sperm chasing their tails

A team led by researchers from Osaka University identify a protein required for electrical signal sensing, which, when defective, causes sperm to swim in circles

A team led by researchers from Osaka University have characterized a protein, called VSP, that keeps sperm swimming in straight lines. Deletion of the...

Life Sciences & Medicine
2019-11-19

Researchers split the “AtoM” in search of a treatment for rheumatoid arthritis

Researchers at Osaka University discover a new type of bone-dissolving osteoclast that contributes to rheumatoid arthritis

Rheumatoid arthritis is a chronic, disabling disease in which the joints become swollen and painfully inflamed. Current treatments can only reduce sym...

Life Sciences & Medicine
2019-11-8

When your microbiome and your genome aren’t a good combination

Researchers led by a team from Osaka University find a link between the gut microbiome, the host genome, and rheumatoid arthritis in Japanese patients

Research carried out by a team led by Osaka University has shown that various Prevotella species, along with several specific genes and biological pat...

Life Sciences & Medicine
2019-10-4

Breaking the Stroma Barrier: Study Shows a New Way to Hit Cancer with Radiation

Researchers at Osaka University test a new cancer treatment in mice that guides high-strength radiotherapy directly to pancreatic tumors

Chemotherapy and radiation therapy are commonly used to treat cancer, but are not always effective and can have toxic side effects. Researchers at Osa...

Life Sciences & Medicine
2019-9-18

Clinical research for PET imaging for prostate cancer begins at Osaka University Hospital

Osaka University Hospital began Japan’s first clinical research for diagnosis of prostate cancer using PET scan results. In this study, the 18F-labell...

Life Sciences & Medicine
2019-8-30

Methylation of microRNA may be a new powerful biomarker for cancer

Researchers from Osaka University find a new way to distinguish individuals with early pancreatic cancer from healthy controls, representing a promising new metric in cancer diagnosis

Researchers from Osaka University found that levels of methylated microRNA were significantly higher in tissue and serum from cancer patients compared...

Life Sciences & Medicine
2019-8-29

First transplantation of iPS cells-derived corneal epithelial cell sheets

Life Sciences & Medicine
2019-8-28

Breast cancer gene a potential target for childhood liver cancer treatment

Researchers from Osaka University find that a gene normally involved in hormone-induced growth of breast cancer cells is also a key player in the development of hepatoblastoma

Hepatoblastoma is a rare liver cancer that mainly affects infants and young children and is associated with mutations in the β-catenin gene. Researche...

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