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Life Sciences & Medicine
2019-11-29

Protein defect leaves sperm chasing their tails

A team led by researchers from Osaka University identify a protein required for electrical signal sensing, which, when defective, causes sperm to swim in circles

A team led by researchers from Osaka University have characterized a protein, called VSP, that keeps sperm swimming in straight lines. Deletion of the...

Life Sciences & Medicine
2019-11-22

Seeing the world’s smallest universal joints

Researchers at Osaka University used electron cryomicroscopy to solve the structure of an essential component of the bacterial flagellum with unprecedented resolution

Researchers at Osaka University used electron cryomicroscopy to produce the most accurate images to date of the bacterial flagellar hook. This work ma...

Natural Sciences
2019-8-28

Terahertz waves reveal hidden processes in ultrafast artificial photosynthesis

Osaka University researchers have succeeded in observing charge transfer and intermolecular interactions in ultrafast artificial photosynthesis. Wit...

Life Sciences & Medicine
2019-8-20

The seeds of Parkinson’s disease: amyloid fibrils that move through the brain

Using X-ray imaging of post mortem brains, researchers find α-synuclein aggregates that can move through the brain before developing into Lewy bodies, the hallmark of Parkinson’s disease

Researchers at Osaka University used microbeam X-ray diffraction to study the ultrastructure of Lewy bodies in post-mortem brains of Parkinson’s disea...

Life Sciences & Medicine
2019-8-9

Multi-tasking protein at the root of neuropathic pain

Researchers from Osaka University find that a protein with roles in neuron development and cell adhesion is also a key factor in pain sensitization

Neuropathic pain is a chronic condition resulting from nerve injury and is characterized by increased pain sensitivity. Although known to be associate...

Life Sciences & Medicine
2019-6-14

Helping select the cells with the most potential

Through investigation of the so-called “Hippo pathway,” researchers at Osaka University have identified a key regulatory mechanism in the development of normal pluripotent embryonic cells

Little is known about the mechanisms by which mammalian cells grow and differentiate during the handful of days between fertilization of the egg and i...

2019-6-11

Successful Construction of Artificial Cell Nuclei Inside of Fertilized Egg, A World First

One Part of the Cell Nuclei Structure Formation Mechanism Elucidated

Life Sciences & Medicine
2019-6-7

Nuclear pore complex outer rings: no longer “one size fits all”

A team led by researchers from Osaka University and NICT finds that, contrary to popular belief, the outer rings of eukaryotic cell nuclear pore complexes are asymmetrical rather than perfectly identical

In eukaryotic cells, molecules can only move into or out of the nucleus through specialized channels called nuclear pore complexes (NPCs). Each NPC ha...

Natural Sciences
2019-5-24

Settling the Debate: Solving the Electronic Surface States of Samarium Hexaboride

Researchers show that the origin of the electronic current on the exterior of samarium hexaboride crystals is due to a kind of symmetry called a “topologically protected surface”

Researchers at Osaka University show that samarium hexaboride is a topological insulator, which allows electrons to flow only along its exterior surfa...

Life Sciences & Medicine
2019-2-19

The key to increased lifespan? Rubicon alters autophagy in animals during aging

Osaka University-led study shows that increased expression of Rubicon in tissues from aged animals contributed to reduced levels of autophagy, which may lead to aging progression

Autophagy is an important biological recycling mechanism that influences the progression of aging in animals. Here, age-related changes in autophagy w...

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