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Life Sciences & Medicine
2018-7-10

Obesity and Inflammation – A Deadly Combination for Prostate Cancer

Osaka University-led study shows how a high-fat diet and systemic inflammation contribute to prostate cancer progression

A new Osaka-centered study identified the mechanisms of high-fat diet (HFD)-induced prostate cancer progression. They observed in a mouse model that H...

Life Sciences & Medicine
2018-7-6

Step-by-Step Account of Systemic Lupus Erythematosus Development Revealed

Osaka University study provides crucial evidence for the pathophysiology of systemic lupus erythematosus

Osaka University researchers elucidated the pathophysiology of systemic lupus erythematosus (SLE), an autoimmune disorder that causes inflammation and...

Life Sciences & Medicine
2018-6-13

SATB1 vital for maintenance of hematopoietic stem cells

Osaka University scientists demonstrate that SATB1 is important for maintaining pluripotency of hematopoietic stem cells

Osaka University-led researchers revealed that expression of SATB1 was involved in both differences in HSC self-renewal ability and differences in the...

Life Sciences & Medicine
2018-6-1

Authentication of patients in medicine via online system should be discussed ethically

Osaka University-led researchers review ethical issues regarding authentication of participants and patients in medical research/treatment using information and communication technology (ICT), proposing two-factor authentication

A group of researchers led by Osaka University indicated that the authentication system for medical research/treatment using ICT needs consideration t...

Life Sciences & Medicine
2018-5-19

Neuron guidance factor found to play a key role in immune cell function

Researchers at Osaka University identify protein that helps maintain energy supplies in immune cells that protect against inflammatory disorders

Macrophages are white blood cells that perform different functions with different energy needs. M2-type macrophages have anti-inflammatory properties ...

2018-4-24

Study sheds light on recently evolved traits among Japanese descendants

Researchers centered at Osaka University identify genetic traits that evolved very recently in human history among Japanese populations

Evolution allows advantageous traits to become predominant. Evolutionary adaptions that occur on comparatively short time scales are less well-underst...

Life Sciences & Medicine
2018-4-19

How adiponectin reduces lipids through exosomes elucidated

2018-4-10

Oxidative stress makes difference between metabolically abnormal and healthy obesities

Life Sciences & Medicine
2018-4-9

Culprit in reducing effectiveness of insulin identified

Scientists at Osaka University discovered that Stromal derived factor-1 (SDF-1) secreted from adipocytes reduced the effectiveness of insulin in adipo...

Life Sciences & Medicine
2018-4-4

New light shed on how bone marrow niches keep stem cells thriving

Japanese researchers uncover cellular factor needed to maintain the environment that regulates hematopoietic stem cells

Hematopoietic stem cells (HSCs) require specialized niches in bone marrow to generate functional blood cells. CAR cells are among cell types located i...

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