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Dietary Yeasts Reduce Inflammation in Central Nerve System via Microflora

Candida kefyr ameliorates experimental autoimmune encephalomyelitis (EAE)

n this study, we sought to determine whether yeasts found in fermented foods have beneficial effects on EAE. Our results suggested that ingestion of C...


Clarification of how exercise helps prevent and treat depression

Exercise increases serotonin levels in the brain

Exercise induces beneficial effects such as hippocampal neurongenesis, a decrease in depression, and improvement of learning behavior....


Clarification of how inflammation causes nerve damage in multiple sclerosis (MS)

The Repulsive Guidance Molecule-a (RGMa) plays a role in neurodegeneration

This group found that one type of T cells, interleukin-17-producing CD4+ T cells (TH17), strongly expressed RGMa....


Relationship between metabolic function and onset of cancer identified

Molecular mechanism links metabolic process and cancer metastasis

External factors (such as smoking and drinking) and inflammation (infection) intertwine and damaged genes accumulate over many years, leading eventual...


Protein affecting development of learning ability identified

α-chimaerin exhibits a wide range of effects on brain functions

Their findings suggest that α-chimaerin is responsible for controlling a wide range of brain functions....


Critical role of Angiopoietin-1 in coronary vein formation clarified

May lead to the development of angiogenic treatments for some heart conditions

Researchers verified the critical role of a angiogenesis growth factor, angiopoietin-1, on coronary vein formation during the development of the heart...


Previously intractable itch relieved in kids with inherited liver disease

Group's findings improve the quality of life for child patients

Researchers have found that phenylbutyrate, a drug for treating a urea cycle defect, reduced the sustained intractable itch in PFIC (Progressive Famil...


Role of Ataxin-2 in development of ALS identified

Contributions to pathogenesis and treatments expected

This group found that Ataxin-2 promotes RNA stability and that genetic mutations in ALS and SCA2 lowered Ataxin-2's capability to stabilize RNA....


Discovery of Mechanism for preventing Ischemic Stroke from deteriorating

RANKL/RANK signaling may be a therapeutic target for treating ischemic stroke.

This group started their research with the assumption that these molecules modified clinical conditions in ischemic stroke....


Olfactory Plays a Key Role in Spatiotemporal Pathogenesis of Cerebral Malaria

Expectations for early diagnosis and new treatment modalities

Given that early detection of even one day of malarial coma could dramatically increase treatment success; this previously unnoticed, truly overlooked...

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