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Breakdown of Neutrophil Protein Causes Severe Autoimmune Disease of Blood Vessels
Osaka University researchers revealed that patients with a severe autoimmune disease that attacks the blood vessels lack the membrane form of a protein ...
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2017
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Bright and Stable: New Acid-Tolerant Green Fluorescent Protein for Bioimaging
Fluorescent proteins (FPs) are powerful tools for visualization of molecular and cellular processes; however, most FPs lose fluorescence at a pH lower than ...
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2017
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CD4 T Cells, Xenobiotic Transporters, and Metabolites in Inflammatory Bowel Diseases
Few studies have investigated the interaction between intestinal T cells with metabolites. Researchers have now shown in mice CD4+ T effector (Teff) cells ...
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2017
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Cellular exclusion of mitochondria protects cells from damage
Researchers from Osaka University identified mitochondrial release out of cells as a novel mechanism by which cells turn over mitochondria and maintain cell ...
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2020
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Dual control: plant peptide hormone generates distinct cell structures for water flow
An international collaboration including Osaka University researchers has found that a peptide hormone regulates two different cell division processes that ...
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2018
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Efflux pump inhibitors: Bulking up to beat bacteria
Researchers from Osaka University used a combination of genetic manipulation and protein structural analysis to determine how the position of “bulky” amino ...
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2022
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Electron Accelerators Reveal the Radical Secrets of Antioxidants
An Osaka University professor has demonstrated for the first time the value of linear particle accelerators for the generation of free radicals inside ...
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2019
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Enzyme’s Unfrozen Adventure: In crystallo protein thermodynamics
Osaka University researchers and collaborators have reported the first in crystallo thermodynamic analysis of copper amine oxidase catalysis using a ...
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2018
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Generation of conjunctivae in a dish
Researchers from Osaka University generated functional conjunctival tissue in a dish. By identifying the protein epidermal growth factor and keratinocyte ...
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2021
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Getting to the "Heart" of Heart Beats: Cardiac thin filament structure and function revealed
Osaka University team uses advanced electron cryomicroscopy and image analysis to reveal the structure of vital muscle thin filaments in the heart with the ...
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2020