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  1. Efflux pump inhibitors: Bulking up to beat bacteria

    Researchers from Osaka University used a combination of genetic manipulation and protein structural analysis to determine how the position of “bulky” amino ...

    Located in Research Info / 2022
  2. Schematic diagrams showing the roles of SNAP23 in pancreatic β cells

    A group of researchers generated pancreatic exocrine- or endocrine-specific SNAP23 knockout mice to investigate the in vivo function of SNAP23 and found that ...

    Located in Research Info / 2016
  3. Role of Molecular Modification in Determining Physical Activity Levels Revealed

    Osaka University-led researchers showed that RNA editing of the molecule CAPS1 is associated with increased dense core vesicle exocytosis, the mechanism by ...

    Located in Research Info / 2016
  4. High-resolution pH Imaging Elucidates Energy Mechanisms in Creating Bacterial Flagella Located in Research Info / 2016
  5. Breakdown of Neutrophil Protein Causes Severe Autoimmune Disease of Blood Vessels

    Osaka University researchers revealed that patients with a severe autoimmune disease that attacks the blood vessels lack the membrane form of a protein ...

    Located in Research Info / 2017
  6. Important Tricyclic Chemical Compounds with Efficient Chirality Control

    Research team of Osaka University synthesized hydronaphtho[1,8-bc]furans, important chiral building blocks for natural-product synthesis. They used a nickel ...

    Located in Research Info / 2017
  7. Osaka University Chemists Unlock the Potential of Fluoroalkenes

    Osaka University-led chemists developed a copper-catalyzed reaction for replacing fluorine atoms with an easily transformable boronate group on polyfluorinated ...

    Located in Research Info / 2017
  8. Pathological Mechanisms in Congenital Myotonic Dystrophy Unveiled

    Congenital myotonic dystrophy (CDM) is a severe form of myotonic dystrophy characterized by muscle fiber immaturity not observed in adult DM, suggesting ...

    Located in Research Info / 2017
  9. How Bacteria Get Their Groove: Mechanism behind Flagellar Motility

    Most motile bacteria move by the use of flagella. While the flagellar motor components have been identified, it remains unclear how they are assembled and ...

    Located in Research Info / 2017
  10. New Strategy for Multiple Myeloma Immunotherapy

    Cancer-specific proteins have been identified for the development of monoclonal antibody (mA)-based therapies, but there remains a need to uncover new targets, ...

    Located in Research Info / 2017
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