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A heat-sensitive calcium channel gets positive feedback
A team of researchers led by Osaka University has found that mutations in the calcium channel protein RyR1 that confer susceptibility to malignant hyperthermia ...
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2022
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A natural amino acid could be a novel treatment for polyglutamine diseases
Researchers from Osaka University, National Center of Neurology and Psychiatry, and Niigata University identified the amino acid arginine as a potential ...
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2020
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A novel, quick, and easy system for genetic analysis of SARS-CoV-2
Osaka/Hokkaido University researchers established a novel PCR-based, bacterium-free reverse genetics system for SARS-CoV-2 using the CPER method, which is ...
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2021
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A simple blood test to identify patients at risk of nonalcoholic fatty liver disease
Researchers from Osaka University, along with international collaborators in Europe, have identified Thrombospondin-2 as a serum biomarker that confirms and ...
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2021
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A vaccine targeting aged cells mitigates metabolic disorders in obese mice
Researchers from Osaka University developed a novel vaccine that removes senescent T cells from adipose tissues. They showed that vaccinated obese mice had ...
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2020
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Alpha-ray missile therapy: tumor cells attacked from intracellular region
Researchers from Osaka University have innovated a technique of irradiating cancer from within. They tagged α-methyl-L-tyrosine, an amino acid, with ...
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2020
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Antioxidant agent may prevent chronic kidney disease and Parkinson’s disease
Researchers from Osaka University developed a novel dietary silicon-based antioxidant agent with renoprotective and neuroprotective effects. They showed in ...
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2020
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Balancing between build-up and break-down of bone
Researchers at Osaka University have shown that SLPI, a secretory leukocyte protease inhibitor, coordinates the mutually contradictory actions of parathyroid ...
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2021
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Cellular exclusion of mitochondria protects cells from damage
Researchers from Osaka University identified mitochondrial release out of cells as a novel mechanism by which cells turn over mitochondria and maintain cell ...
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2020
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Change isn’t a good thing for Japanese rheumatoid arthritis patients
Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA) that dramatically increases the risk of death. In a recent study led by ...
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2020
