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Liver cancer cells manipulate stromal cells involved in fibrosis to promote tumor growth
Researchers led by Osaka University have found that liver cancer cells induce autophagy in hepatic stellate cells, causing them to produce a growth factor ...
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2020
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Alpha-ray missile therapy: tumor cells attacked from intracellular region
Researchers from Osaka University have innovated a technique of irradiating cancer from within. They tagged α-methyl-L-tyrosine, an amino acid, with ...
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2020
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Meet the Smurfs: A bone metabolism family
Researchers from Osaka University and Ehime University have found that protein Smurf2 can regulate a cellular pathway that affects bone metabolism. Smurf2 can ...
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2020
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Supersaturation: the barrier between protein folding and misfolding
It’s commonly accepted that protein folding/misfolding are alternative reactions of unfolded proteins but the principles governing this remain unknown. Here, ...
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2021
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Generation of conjunctivae in a dish
Researchers from Osaka University generated functional conjunctival tissue in a dish. By identifying the protein epidermal growth factor and keratinocyte ...
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2021
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How hepatitis C virus evades the immune system
Researchers from Osaka University unpicked how hepatitis C virus (HCV) and human cytomegalovirus (HCMV) evade the immune system to cause chronic infection. By ...
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2021
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Unforeseen links to chronic pancreatitis found in cancer-related signals
Researchers from Osaka University have demonstrated that two signaling pathways, the PI3K and the Hippo pathways earlier implicated in the development of ...
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2021
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The molecular underpinnings of immune cell migration
Researchers from Osaka University discovered a novel molecular mechanism by which immune cells migrate and reach sites of infection. By studying dendritic ...
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2021
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From symmetry to asymmetry: the two sides of life
Researchers from Osaka University used innovative imaging techniques to demonstrate symmetric collective alignment of nuclei in the muscle cells of the ...
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2021
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A simple blood test to identify patients at risk of nonalcoholic fatty liver disease
Researchers from Osaka University, along with international collaborators in Europe, have identified Thrombospondin-2 as a serum biomarker that confirms and ...
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2021
