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My heart will go on: patient-derived heart cells mimic disease in vitro
Researchers from Osaka University have found that induced pluripotent stem cell–derived cardiomyocytes from a patient with arrhythmogenic cardiomyopathy ...
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2022
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Drug-resistant bacteria flaunt their curves
Researchers from Osaka University have found that applying deep learning to electron microscope images can distinguish drug-resistant bacteria from ...
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2022
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A heat-sensitive calcium channel gets positive feedback
A team of researchers led by Osaka University has found that mutations in the calcium channel protein RyR1 that confer susceptibility to malignant hyperthermia ...
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2022
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Hickory dickory dock, the bean bug brain’s biological clock
Researchers from Osaka University have found that photoperiod variation in bean bugs is regulated by genes involved in maintaining circadian rhythm via the ...
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2022
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Deadly piston pump: how a colonization factor is secreted by bacterial type 4 pili
Researchers from Osaka University have found that the Vibrio cholerae colonization factor TcpF forms a flower-shaped trimer to specifically bind to the minor ...
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2022
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Huntington’s disease-causing DNA repeat mutations reversed in the lab
An international team of researchers identifies a compound that corrects genetic abnormalities involved in the onset and progression of Huntington’s disease ...
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2020
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How tissues harm themselves during wound healing
Researchers from Osaka University discovered that increased expression of Rbm7 in apoptotic tissue cells results in the recruitment of ...
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2020
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Modeling the human eye in a dish
Researchers from Osaka University developed and validated a novel PITX2-eGFP hiPSC reporter line to model the development of periocular mesenchymal cells. ...
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2020
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A natural amino acid could be a novel treatment for polyglutamine diseases
Researchers from Osaka University, National Center of Neurology and Psychiatry, and Niigata University identified the amino acid arginine as a potential ...
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2020
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A vaccine targeting aged cells mitigates metabolic disorders in obese mice
Researchers from Osaka University developed a novel vaccine that removes senescent T cells from adipose tissues. They showed that vaccinated obese mice had ...
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2020
