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Immunotherapy and Diabetes: A Game of Hide and Seek?
Immune checkpoint inhibitors (ICIs) are emerging as an effective treatment for certain cancers, but in rare cases can cause autoimmune diseases. Researchers at ...
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2019
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Interregional differences in somatic genetic landscape diversify prognosis in glioblastoma
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2019
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Is turning back the clock in aging fat cells a remedy for lifestyle diseases?
Researchers from Osaka University found that lifestyle diseases such as diabetes, high cholesterol, and fatty liver are caused by age-related changes in fat ...
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2020
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It’s in our genome: Uncovering clues to longevity from human genetics
Researchers from Osaka University found that high blood pressure and obesity are the strongest factors reducing lifespan based on genetic and clinical ...
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2020
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Japanese Study Finds Concerning Trends in Cervical Cancer and Treatment Response
Osaka University-centered research examined a large-scale Japanese data cohort for trends in cervical cancer prevalence, treatment, and survival. They ...
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2019
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Keep quiet or be eliminated: how cell competition modulates morphogen gradients
Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allows them to ...
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2019
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Key to beating colorectal cancer hiding in plain sight?
Colorectal cancer, one of the most common cancers in the developed world, is intrinsically resistant to many drug therapies. In an attempt to identify novel ...
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2020
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Link discovered between male infertility and self-eating
Sertoli cells are important for spermatogenesis. Researchers at Osaka University have uncovered a novel regulatory mechanism of Sertoli cell function. ...
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2021
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Liver cancer cells manipulate stromal cells involved in fibrosis to promote tumor growth
Researchers led by Osaka University have found that liver cancer cells induce autophagy in hepatic stellate cells, causing them to produce a growth factor ...
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2020
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Lung Neuropeptide Exacerbates Lethal Influenza Virus Infection
Researchers found that lung immune cells (phagocytes) produce increased levels of neuropeptide Y (NPY) when mice are infected with severe influenza virus. NPY ...
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2018
