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Resist! TAK1 enables endothelial cells to avoid apoptosis
TNFα-induced cell death is tightly regulated and resisted in endothelial cells. Here, an Osaka University-led research team used a unique type of mouse, in ...
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2019
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Small Metabolites Have Big Effects on the Intestinal Immune Response
Normal gut bacteria are instrumental in inducing an immune response in the presence of invading pathogens. However, exactly how commensal bacteria cause ...
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2019
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The making of memory B cells and long-term immune responses
Researchers at Osaka University in Japan have identified two factors necessary for the production of memory B cells, the cells of the immune system that allow ...
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2020
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The Mincle receptor provides protective immunity against Group A Streptococcus
Group A Streptococcus (GAS) causes invasive infections that result in high mortality. Despite being susceptible to many antibiotics, GAS continues to cause ...
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2018
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When Good Cells Go Bad: Regulating the MS-Causing Properties of Th17 Cells
Multiple sclerosis (MS) and other inflammatory autoimmune diseases are characterized by localized inflammation in various tissues, including the brain. Using a ...
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2019
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When your microbiome and your genome aren’t a good combination
Research carried out by a team led by Osaka University has shown that various Prevotella species, along with several specific genes and biological pathways, ...
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2019
