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My heart will go on: patient-derived heart cells mimic disease in vitro
Researchers from Osaka University have found that induced pluripotent stem cell–derived cardiomyocytes from a patient with arrhythmogenic cardiomyopathy ...
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2022
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Up to our NECs in it: in-depth genomic analysis of a rare carcinoma
Researchers from Osaka University have performed comprehensive genomic analysis of tissue samples from a large group of patients with neuroendocrine carcinoma ...
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2021
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Redefining human diseases through the lens of your DNA
Osaka University and Harvard Medical School researchers performed genome-wide analysis studies (GWAS) to identify genetic elements associated with various ...
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2021
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It's not all-right: problems when your body doesn't recognize your own left-handed RNA
By generating a specific mutation in lab mice, Osaka University researchers determined that a protein domain in an enzyme called adenosine deaminase 1 p150 is ...
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2021
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Study on chromosomal rearrangements in yeast reveals potential avenue for cancer therapy
Researchers from Osaka University have found that the attachment of a ubiquitin molecule to a protein called PCNA at the lysine 107 position causes gross ...
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2021
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From symmetry to asymmetry: the two sides of life
Researchers from Osaka University used innovative imaging techniques to demonstrate symmetric collective alignment of nuclei in the muscle cells of the ...
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2021
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A novel, quick, and easy system for genetic analysis of SARS-CoV-2
Osaka/Hokkaido University researchers established a novel PCR-based, bacterium-free reverse genetics system for SARS-CoV-2 using the CPER method, which is ...
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2021
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Brain seasonality: Bean bug neurons need biological clock gene for seasonal egg-laying
Researchers from Osaka University have found that a biological clock gene is needed in bean bugs for seasonal egg-laying. The clock gene regulates egg-laying ...
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2021
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Alpha-ray missile therapy: tumor cells attacked from intracellular region
Researchers from Osaka University have innovated a technique of irradiating cancer from within. They tagged α-methyl-L-tyrosine, an amino acid, with ...
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2020
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A library of mice to look up the best liver cancer treatment
Researchers from Osaka University have developed a mouse model that reproduces the real-world variety of genetic drivers of liver cancer, and used this model ...
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2020