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Phosphorylation of Regnase-1 Lets IL-17 Run Amok
A research team led by Osaka University found that the cytokine interleukin (IL)-17 triggers the phosphorylation of mRNA-degrading enzyme Regnase-1, resulting ...
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2019
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Reading the Signs: Semaphorin Linked to Lung Cancer Treatment Resistance
Osaka University researchers showed that high levels of the protein Semaphorin 7a are associated with resistance to treatment with EGFR-TKIs in lung ...
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2018
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Redefining human diseases through the lens of your DNA
Osaka University and Harvard Medical School researchers performed genome-wide analysis studies (GWAS) to identify genetic elements associated with various ...
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2021
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Regulator of Chromosome Structure Crucial to Healthy Brain Function and Nerve Development
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2017
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Repair full of mistakes may develop cancer!?
A group of researchers found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain, and a ...
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2016
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Researchers discover key mechanism of DNA replication
Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how ...
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2018
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Researchers split the “AtoM” in search of a treatment for rheumatoid arthritis
Rheumatoid arthritis is a chronic, disabling disease in which the joints become swollen and painfully inflamed. Current treatments can only reduce symptoms or ...
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2019
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Rethinking Existing Method Opens New Doors for Cancer Diagnostics
Osaka University researchers overcame limitations of current DNA sequencers by using current-tunneling measurements to measure the base sequence and quantities ...
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2018
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RNA quality control system goes awry in frontotemporal lobar degeneration
Researchers from Osaka University have uncovered that the RNA exosome is critical for the degradation of defective repeat RNA derived from C9orf72 repeat ...
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2020
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Role of Molecular Modification in Determining Physical Activity Levels Revealed
Osaka University-led researchers showed that RNA editing of the molecule CAPS1 is associated with increased dense core vesicle exocytosis, the mechanism by ...
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2016