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Huntington’s disease-causing DNA repeat mutations reversed in the lab
An international team of researchers identifies a compound that corrects genetic abnormalities involved in the onset and progression of Huntington’s disease ...
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2020
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A tadpole with a twist: Left–right asymmetric development of Oikopleura dioica
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2020
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A natural amino acid could be a novel treatment for polyglutamine diseases
Researchers from Osaka University, National Center of Neurology and Psychiatry, and Niigata University identified the amino acid arginine as a potential ...
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2020
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The protein that stands between us and autoimmunity
Researchers from Osaka University identified the epigenetic proteins Tet2 and Tet3 as key regulators of B cell function. They showed that these proteins ...
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2020
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Change isn’t a good thing for Japanese rheumatoid arthritis patients
Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA) that dramatically increases the risk of death. In a recent study led by ...
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2020
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RNA quality control system goes awry in frontotemporal lobar degeneration
Researchers from Osaka University have uncovered that the RNA exosome is critical for the degradation of defective repeat RNA derived from C9orf72 repeat ...
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2020
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DNA repair supports brain cognitive development
Researchers at Osaka University showed that the enzyme Polβ functions in genome maintenance by preventing double-stranded breaks in DNA during brain ...
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2020
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A library of mice to look up the best liver cancer treatment
Researchers from Osaka University have developed a mouse model that reproduces the real-world variety of genetic drivers of liver cancer, and used this model ...
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2020
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Alpha-ray missile therapy: tumor cells attacked from intracellular region
Researchers from Osaka University have innovated a technique of irradiating cancer from within. They tagged α-methyl-L-tyrosine, an amino acid, with ...
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2020
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From symmetry to asymmetry: the two sides of life
Researchers from Osaka University used innovative imaging techniques to demonstrate symmetric collective alignment of nuclei in the muscle cells of the ...
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2021
