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Location is everything for plant cell differentiation
During development, plant cell differentiation is guided by location rather than lineage. Now, researchers from Osaka University have shown that the ...
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2019
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Mechanism of familial Parkinson’s disease clarified in fruit fly model
Parkinson’s disease (PD) is a common neurodegenerative disorder, in which 15% of cases are linked to genetic mutations. The DNAJC13 gene has been linked to a ...
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2018
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Methylation of microRNA may be a new powerful biomarker for cancer
Researchers from Osaka University found that levels of methylated microRNA were significantly higher in tissue and serum from cancer patients compared with ...
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2019
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Multidrug resistance: Not as recent as we thought
Researchers from Osaka University found that the ancient RND-type multidrug efflux pump AcrB from Haemophilus influenzae targets the same drugs as its more ...
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2019
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My heart will go on: patient-derived heart cells mimic disease in vitro
Researchers from Osaka University have found that induced pluripotent stem cell–derived cardiomyocytes from a patient with arrhythmogenic cardiomyopathy ...
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2022
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New genome-editing method “cuts back” on unwanted genetic mutations
Gene therapy can potentially correct genetic disorders by directly editing defective genes. CRISPR-Cas9 is a popular gene-editing technology whose clinical ...
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2018
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New Integrated Analytical Approach Reveals Molecules Involved in Disease
Osaka University researchers developed a novel method of identifying disease-related molecules and processes. They achieved this by integrating genetic data ...
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2018
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New light shed on how bone marrow niches keep stem cells thriving
Hematopoietic stem cells (HSCs) require specialized niches in bone marrow to generate functional blood cells. CAR cells are among cell types located in niches, ...
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2018
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New methods of enhancing efficiency of genetic engineering in mice and rats developed
A group of researchers developed two new gene modification methods: lsODN and 2H2OP. These methods will increase the efficiency of genetic engineering in mice ...
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2016
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Obesity and Inflammation – A Deadly Combination for Prostate Cancer
A new Osaka-centered study identified the mechanisms of high-fat diet (HFD)-induced prostate cancer progression. They observed in a mouse model that HFD ...
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2018
