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Formidable duo: protective effect of CD9 and CD81 in COPD and accelerated aging
Chronic obstructive pulmonary disease (COPD) is a disease of accelerated lung aging, but the mechanism remains unclear. Osaka University-centered researchers ...
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2018
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New light shed on how bone marrow niches keep stem cells thriving
Hematopoietic stem cells (HSCs) require specialized niches in bone marrow to generate functional blood cells. CAR cells are among cell types located in niches, ...
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2018
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Study sheds light on recently evolved traits among Japanese descendants
Evolution allows advantageous traits to become predominant. Evolutionary adaptions that occur on comparatively short time scales are less well-understood. ...
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2018
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Rethinking Existing Method Opens New Doors for Cancer Diagnostics
Osaka University researchers overcame limitations of current DNA sequencers by using current-tunneling measurements to measure the base sequence and quantities ...
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2018
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Key Protein Providing Defense Against “Jumping Genes” Identified
International researchers revealed the crucial function of the protein HP1a for piRNA biogenesis, which is important for transposon silencing. Transposons are ...
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2018
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Obesity and Inflammation – A Deadly Combination for Prostate Cancer
A new Osaka-centered study identified the mechanisms of high-fat diet (HFD)-induced prostate cancer progression. They observed in a mouse model that HFD ...
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2018
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Researchers discover key mechanism of DNA replication
Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how ...
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2018
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New Integrated Analytical Approach Reveals Molecules Involved in Disease
Osaka University researchers developed a novel method of identifying disease-related molecules and processes. They achieved this by integrating genetic data ...
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2018
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Reading the Signs: Semaphorin Linked to Lung Cancer Treatment Resistance
Osaka University researchers showed that high levels of the protein Semaphorin 7a are associated with resistance to treatment with EGFR-TKIs in lung ...
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2018
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Keeping Chromosomes in Check: A New Role for Heterochromatin
Large changes in the structure of chromosomes are usually fatal for the cell or can lead to genetic diseases such as cancer. Many large chromosomal ...
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2019
