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New computational method reveals chemoresistance drug targets
The methylation of deoxycytosine to form 5-methylcytosine (5mC) is an important feature of cancer. Extensive DNA methylation and transcription analyses have ...
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2018
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New method uses just a drop of blood to monitor lung cancer treatment
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2018
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New Strategy for Multiple Myeloma Immunotherapy
Cancer-specific proteins have been identified for the development of monoclonal antibody (mA)-based therapies, but there remains a need to uncover new targets, ...
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2017
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Obesity and Inflammation – A Deadly Combination for Prostate Cancer
A new Osaka-centered study identified the mechanisms of high-fat diet (HFD)-induced prostate cancer progression. They observed in a mouse model that HFD ...
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2018
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Peering into the genome of brain tumor
Scientists at Osaka University have created a machine learning method for classifying the mutations of glioma brain tumors based on MR images alone. Thus far, ...
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2020
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Pumping Iron Could Save Your Life
Researchers from Osaka University have found that sarcopenia, a condition characterized by decreased skeletal muscle mass, is strongly associated with poor ...
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2019
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Reading the Signs: Semaphorin Linked to Lung Cancer Treatment Resistance
Osaka University researchers showed that high levels of the protein Semaphorin 7a are associated with resistance to treatment with EGFR-TKIs in lung ...
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2018
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Resist! TAK1 enables endothelial cells to avoid apoptosis
TNFα-induced cell death is tightly regulated and resisted in endothelial cells. Here, an Osaka University-led research team used a unique type of mouse, in ...
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2019
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Rethinking Existing Method Opens New Doors for Cancer Diagnostics
Osaka University researchers overcame limitations of current DNA sequencers by using current-tunneling measurements to measure the base sequence and quantities ...
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2018
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Safety of novel cancer-specific PET probe confirmed in clinical research
In first-in-human clinical studies, researchers at Osaka University confirmed the safety of F-18 NKO-035, a new PET probe that specifically binds to LAT1 ...
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2019