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A Real Turn On: Evolutionary Rotation of Fly Genitalia Tied to Mating Success
Osaka University researchers sought evidence that developmental genital rotation of flies in the order Diptera evolved in correlation with a shift to ...
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2019
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Small Metabolites Have Big Effects on the Intestinal Immune Response
Normal gut bacteria are instrumental in inducing an immune response in the presence of invading pathogens. However, exactly how commensal bacteria cause ...
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2019
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Big Data Provides Clues for Characterizing Immunity in Japanese
Osaka University researchers used various sets of large-scale data to characterize the variation and phenotypic associations of an immunity-related gene region ...
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2019
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Large-scale Study Reveals Genetic Risk of Diabetes in the Japanese Population
Researchers at Osaka University, The University of Tokyo, RIKEN, and others performed a meta-analysis using data on over 36,000 Japanese sufferers of type 2 ...
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2019
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More Physical Than Chemical: Researchers Show What Really Gets Cells Going
Collective cell migration is essential in many organisms, with roles in human cellular processes including cancer invasion and wound healing. Now, a team led ...
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2019
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When Good Cells Go Bad: Regulating the MS-Causing Properties of Th17 Cells
Multiple sclerosis (MS) and other inflammatory autoimmune diseases are characterized by localized inflammation in various tissues, including the brain. Using a ...
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2019
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The key to increased lifespan? Rubicon alters autophagy in animals during aging
Autophagy is an important biological recycling mechanism that influences the progression of aging in animals. Here, age-related changes in autophagy were ...
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2019
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Treatment to a T? Taking a BiTE Out of Lung Cancer
An Osaka University-led research team assayed T cell cytotoxicity in tumor tissue in lung cancer, along with normal lung tissue and peripheral blood. They ...
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2019
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Gut Instinct: Bile Acid-Triggered Bacterial Adaptation Characterized
An international team led by Osaka University researchers has shown how the Salmonella protein RamR senses bile acids present in the gut, leading to the ...
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2019
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Hematopoietic Stem Cells: Making Blood Thicker than Water
An Osaka University-led team revealed that Ragnase-1 is a key regulator of the self-renewal and differentiation of hematopoietic stem and progenitor cells. ...
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2019