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CD4 T Cells, Xenobiotic Transporters, and Metabolites in Inflammatory Bowel Diseases
Few studies have investigated the interaction between intestinal T cells with metabolites. Researchers have now shown in mice CD4+ T effector (Teff) cells ...
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2017
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Bright and Stable: New Acid-Tolerant Green Fluorescent Protein for Bioimaging
Fluorescent proteins (FPs) are powerful tools for visualization of molecular and cellular processes; however, most FPs lose fluorescence at a pH lower than ...
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2017
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Magnesium makes chromosomes
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2018
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Photosynthesis Involves a Protein “Piston”
The photosystem I (PSI)–ferrodoxin (Fd) complex is important in electron transfer during photosynthesis, through which plants convert sunlight, carbon dioxide, ...
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2018
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Accepted or Rejected? Uncovering How Fate of B Cell is Determined
Osaka University-centered researchers identify the plasma cell-prone B cells in the light zone of germinal centers. Higher expression of the proteins ICAM-1 ...
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2018
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Igniting the Rheumatoid Arthritis Flame Through A Cellular Cascade
Osaka University-led international researchers identified a network of cells responsible for secretion of a key inflammatory cytokine in development of ...
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2018
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New approach to treating infectious diseases as an alternative to antibiotics
Osaka University-led researchers clarified how pathogenic E. coli bacteria attached to the host intestinal epithelium. They revealed that type IV pili on the ...
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2018
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Step-by-Step Account of Systemic Lupus Erythematosus Development Revealed
Osaka University researchers elucidated the pathophysiology of systemic lupus erythematosus (SLE), an autoimmune disorder that causes inflammation and tissue ...
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2018
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Autonomous gene expression control nanodevice will contribute to medical care
Osaka University-led researchers constructed integrated gene logic-chips called "gene nanochips." These self-contained nanochips can switch genes on or off ...
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2018
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Brain cancer potentially resists immunotherapies by trapping T cells in bone marrow
Researchers in collaboration with Osaka University found that brain tumors in mice and humans cause immune T-cells to become trapped in bone marrow. This ...
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2018
