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精子形成における遺伝子制御の謎を解明
大阪大学大学院生命機能研究科の井木太一郎助教と甲斐歳恵教授らの研究グループは、ショウジョウバエをモデルにした研究において、多くの生物が保持しているCyclophilin40「Cyp40」※1 というタンパク質が精子をつくるために不可欠な因子であり、microRNA「miRNA」※2 ...
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大阪大学発 自慢の研究をあなたに
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2020
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Elucidating the mechanism of pathogenesis by chromosome duplication for neurodevelopmental disorders
A group of researchers was the first in the world to discover the neurodevelopmental disorder-causing molecule micro RNA-484 (miR-484) produced by the ...
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2016
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Embryonic microRNA-369 controls metabolic splicing factors and urges cellular reprogramming
A research team found a unique role of the embryonic miR-369-HNRNPA2B1 axis in controlling metabolic enzyme function. The data suggests a novel pathway linking ...
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2015
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Sequencing multiple RNA base modifications simultaneously: a new era of RNA biology
Researchers at Osaka University used a single-molecule quantum sequencer to sequence microRNA molecules isolated from colorectal cancer cells and to detect two ...
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2021
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Treating inflammatory bowel disorder by delivering microRNAs
Osaka University researchers efficiently delivered miRNAs to immune response cells in inflamed intestinal tracts using a super carbonate apatite (sCA), which ...
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2018
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Whole blood RNA profiling of severe COVID-19 cases
Researchers led by Osaka University performed RNA-sequencing analysis of whole blood samples from patients with severe COVID-19 and healthy controls to ...
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2022
