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Formation site of autophagosomal membranes identified
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2013
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Elucidation of role for active Vitamin D in maintenance of bone homeostasis
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2013
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Elucidation of 3D Structure of Protein That Can Eliminate Alzheimer’s Disease-Causing Agent
SorLA/LR11 is a unique neuronal sorting receptor considered to be a major genetic risk factor for Alzheimer’s disease. We have recently reported that it ...
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2015
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Key to the development of fundamental treatment methods for Parkinson's disease
A group of researchers succeeded in elucidating the secondary structure of Lewy bodies (LBs) in the brain of Parkinson’s disease (PD) patients for the first ...
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2015
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Successful 1,000-fold enhancement of reaction velocity constants for proteins’ change into toxic substances
A group of researchers succeeded in increasing the velocity constant for a reaction in which proteins causing Alzheimer disease (AD) turn into toxic substances ...
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2016
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Genetic factors of esophageal cancer commonly found among Japanese population discovered
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2016
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Developing New Therapeutics For Parkinson's Disease
A group of researchers presented data which reveals that necdin promotes mitochondrial biogenesis through stabilization of endogenous PGC-1α to exert ...
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2016
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New hepatitis C virus mechanism elucidated
A group of researchers identified a new drug target capable of suppressing the propagation of the hepatitis C virus (HCV), improving HCV pathologic conditions, ...
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2016
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Discovery of biomarkers for the prognosis of chronic kidney disease
A group of researchers found that measuring D-amino acids, which present only traces in human, provides prognostic information of chronic kidney disease (CKD). ...
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2016
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Japanese researchers find why Alzheimer’s drugs work in the lab but not in patients
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2017