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Multidrug resistance: Not as recent as we thought
Researchers from Osaka University found that the ancient RND-type multidrug efflux pump AcrB from Haemophilus influenzae targets the same drugs as its more ...
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2019
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New Method Increases Accuracy of Nontuberculous Mycobacteria Identification
The more than 200 species of nontuberculous mycobacteria (NTM) are notoriously difficult to differentiate, delaying the implementation of targeted antibiotic ...
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2019
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Winning the Arms Race: Analysis Reveals Key Gene for Bacterial Infection
Researchers at Osaka University applied molecular evolutionary analysis to quantify the severity of negative selection pressures on genes encoding the ...
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2019
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Japanese Study Finds Concerning Trends in Cervical Cancer and Treatment Response
Osaka University-centered research examined a large-scale Japanese data cohort for trends in cervical cancer prevalence, treatment, and survival. They ...
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2019
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Novel viral identification method developed
A research team led by Osaka University created a novel nanobio device for single-virus detections by combining a nanopore sensor with peptide bioengineering. ...
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2019
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Lung Neuropeptide Exacerbates Lethal Influenza Virus Infection
Researchers found that lung immune cells (phagocytes) produce increased levels of neuropeptide Y (NPY) when mice are infected with severe influenza virus. NPY ...
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2018
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Threat of “nightmare bacteria” exhibiting resistance to last-resort antibiotic colistin
Researchers examined the dissemination of colistin-resistant bacteria among residents of rural communities in Vietnam to find that the prevalence of ...
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2018
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Going viral: New cells for norovirus production in the lab
Human norovirus is a major cause of infections that can be particularly dangerous to children and elderly people. Here, an Osaka University-led research team ...
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2018
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How low can we go? Nanopore detection of single flu viruses to control outbreaks
Influenza is a highly contagious respiratory disease that may cause a serious outbreak at any time. Here, an Osaka University-led research team developed a new ...
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2018
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The Mincle receptor provides protective immunity against Group A Streptococcus
Group A Streptococcus (GAS) causes invasive infections that result in high mortality. Despite being susceptible to many antibiotics, GAS continues to cause ...
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2018