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Igniting the Rheumatoid Arthritis Flame Through A Cellular Cascade
Osaka University-led international researchers identified a network of cells responsible for secretion of a key inflammatory cytokine in development of ...
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2018
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Immune responses against pathogens are efficiently induced through cytosolic distribution of interferon-inducible guanylate binding proteins
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2017
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Immunotherapy and Diabetes: A Game of Hide and Seek?
Immune checkpoint inhibitors (ICIs) are emerging as an effective treatment for certain cancers, but in rare cases can cause autoimmune diseases. Researchers at ...
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2019
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Neuron guidance factor found to play a key role in immune cell function
Macrophages are white blood cells that perform different functions with different energy needs. M2-type macrophages have anti-inflammatory properties that may ...
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2018
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New method uses just a drop of blood to monitor lung cancer treatment
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2018
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New Strategy for Multiple Myeloma Immunotherapy
Cancer-specific proteins have been identified for the development of monoclonal antibody (mA)-based therapies, but there remains a need to uncover new targets, ...
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2017
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No more aggravation: ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis
Osaka University researchers identified a mechanism underlying prevention of microbial metabolite-induced colitis. A protein called E-NTPD8 breaks down ATP ...
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2021
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Non-invasive microscopy detects activation state and distinguishes between cell types
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2019
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Novel Small Antibody Fragment: A Valuable Tool in Crystallography
Achieving quality diffracting crystals remains the major bottleneck in macromolecular x-ray crystallography. Antibody fragments have been used to aid ...
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2017
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Step-by-Step Account of Systemic Lupus Erythematosus Development Revealed
Osaka University researchers elucidated the pathophysiology of systemic lupus erythematosus (SLE), an autoimmune disorder that causes inflammation and tissue ...
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2018
