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Igniting the Rheumatoid Arthritis Flame Through A Cellular Cascade
Osaka University-led international researchers identified a network of cells responsible for secretion of a key inflammatory cytokine in development of ...
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2018
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Step-by-Step Account of Systemic Lupus Erythematosus Development Revealed
Osaka University researchers elucidated the pathophysiology of systemic lupus erythematosus (SLE), an autoimmune disorder that causes inflammation and tissue ...
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2018
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Brain cancer potentially resists immunotherapies by trapping T cells in bone marrow
Researchers in collaboration with Osaka University found that brain tumors in mice and humans cause immune T-cells to become trapped in bone marrow. This ...
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2018
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New method uses just a drop of blood to monitor lung cancer treatment
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2018
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Non-invasive microscopy detects activation state and distinguishes between cell types
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2019
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Big Data Provides Clues for Characterizing Immunity in Japanese
Osaka University researchers used various sets of large-scale data to characterize the variation and phenotypic associations of an immunity-related gene region ...
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2019
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Immunotherapy and Diabetes: A Game of Hide and Seek?
Immune checkpoint inhibitors (ICIs) are emerging as an effective treatment for certain cancers, but in rare cases can cause autoimmune diseases. Researchers at ...
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2019
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How hepatitis C virus evades the immune system
Researchers from Osaka University unpicked how hepatitis C virus (HCV) and human cytomegalovirus (HCMV) evade the immune system to cause chronic infection. By ...
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2021
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The molecular underpinnings of immune cell migration
Researchers from Osaka University discovered a novel molecular mechanism by which immune cells migrate and reach sites of infection. By studying dendritic ...
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2021
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No more aggravation: ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis
Osaka University researchers identified a mechanism underlying prevention of microbial metabolite-induced colitis. A protein called E-NTPD8 breaks down ATP ...
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2021