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Dibenzoazepine Defender: Drug Found to be Effective Against Resistant Hepatitis C
Chronic hepatitis C infection can lead to serious liver diseases. Antivirals that directly target hepatitis C virus (HCV) proteins are effective, but novel ...
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2017
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DNA repair supports brain cognitive development
Researchers at Osaka University showed that the enzyme Polβ functions in genome maintenance by preventing double-stranded breaks in DNA during brain ...
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2020
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Formidable duo: protective effect of CD9 and CD81 in COPD and accelerated aging
Chronic obstructive pulmonary disease (COPD) is a disease of accelerated lung aging, but the mechanism remains unclear. Osaka University-centered researchers ...
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2018
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From symmetry to asymmetry: the two sides of life
Researchers from Osaka University used innovative imaging techniques to demonstrate symmetric collective alignment of nuclei in the muscle cells of the ...
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2021
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Huntington’s disease-causing DNA repeat mutations reversed in the lab
An international team of researchers identifies a compound that corrects genetic abnormalities involved in the onset and progression of Huntington’s disease ...
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2020
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It's not all-right: problems when your body doesn't recognize your own left-handed RNA
By generating a specific mutation in lab mice, Osaka University researchers determined that a protein domain in an enzyme called adenosine deaminase 1 p150 is ...
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2021
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Keep quiet or be eliminated: how cell competition modulates morphogen gradients
Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allows them to ...
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2019
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Keeping Chromosomes in Check: A New Role for Heterochromatin
Large changes in the structure of chromosomes are usually fatal for the cell or can lead to genetic diseases such as cancer. Many large chromosomal ...
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2019
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Key Protein Providing Defense Against “Jumping Genes” Identified
International researchers revealed the crucial function of the protein HP1a for piRNA biogenesis, which is important for transposon silencing. Transposons are ...
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2018
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Large-scale Study Reveals Genetic Risk of Diabetes in the Japanese Population
Researchers at Osaka University, The University of Tokyo, RIKEN, and others performed a meta-analysis using data on over 36,000 Japanese sufferers of type 2 ...
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2019
