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My heart will go on: patient-derived heart cells mimic disease in vitro
Researchers from Osaka University have found that induced pluripotent stem cell–derived cardiomyocytes from a patient with arrhythmogenic cardiomyopathy ...
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2022
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New methods of enhancing efficiency of genetic engineering in mice and rats developed
A group of researchers developed two new gene modification methods: lsODN and 2H2OP. These methods will increase the efficiency of genetic engineering in mice ...
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2016
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Repair full of mistakes may develop cancer!?
A group of researchers found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain, and a ...
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2016
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Role of Molecular Modification in Determining Physical Activity Levels Revealed
Osaka University-led researchers showed that RNA editing of the molecule CAPS1 is associated with increased dense core vesicle exocytosis, the mechanism by ...
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2016
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Calcium Aids Chromosome Condensation Prior to Cell Division
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2016
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Regulator of Chromosome Structure Crucial to Healthy Brain Function and Nerve Development
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2017
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Dibenzoazepine Defender: Drug Found to be Effective Against Resistant Hepatitis C
Chronic hepatitis C infection can lead to serious liver diseases. Antivirals that directly target hepatitis C virus (HCV) proteins are effective, but novel ...
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2017
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Mechanism of familial Parkinson’s disease clarified in fruit fly model
Parkinson’s disease (PD) is a common neurodegenerative disorder, in which 15% of cases are linked to genetic mutations. The DNAJC13 gene has been linked to a ...
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2018
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New genome-editing method “cuts back” on unwanted genetic mutations
Gene therapy can potentially correct genetic disorders by directly editing defective genes. CRISPR-Cas9 is a popular gene-editing technology whose clinical ...
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2018
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Study reveals genetic basis of quantitative traits and diseases in Japanese
Osaka University-centered researchers presented one of the largest non-European genome-wide association study (GWAS) of quantitative biological traits to date, ...
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2018
