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Hematopoietic Stem Cells: Making Blood Thicker than Water
An Osaka University-led team revealed that Ragnase-1 is a key regulator of the self-renewal and differentiation of hematopoietic stem and progenitor cells. ...
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2019
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Location is everything for plant cell differentiation
During development, plant cell differentiation is guided by location rather than lineage. Now, researchers from Osaka University have shown that the ...
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2019
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Phosphorylation of Regnase-1 Lets IL-17 Run Amok
A research team led by Osaka University found that the cytokine interleukin (IL)-17 triggers the phosphorylation of mRNA-degrading enzyme Regnase-1, resulting ...
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2019
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Nuclear pore complex outer rings: no longer “one size fits all”
In eukaryotic cells, molecules can only move into or out of the nucleus through specialized channels called nuclear pore complexes (NPCs). Each NPC has a ring ...
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2019
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Helping select the cells with the most potential
Little is known about the mechanisms by which mammalian cells grow and differentiate during the handful of days between fertilization of the egg and ...
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2019
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Keep quiet or be eliminated: how cell competition modulates morphogen gradients
Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allows them to ...
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2019
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Researchers discover molecular light switch in photoreceptor cells
Transducin, a protein found inside photoreceptor cells in vertebrate eyes, alters its cellular location in response to changes in light intensity, allowing our ...
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2019
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Researchers split the “AtoM” in search of a treatment for rheumatoid arthritis
Rheumatoid arthritis is a chronic, disabling disease in which the joints become swollen and painfully inflamed. Current treatments can only reduce symptoms or ...
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2019
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Genomic cut and paste using a Class 1 CRISPR system
Repairing faulty genes to prevent and cure disease is something researchers have been working towards for many years. While Class 2 CRISPR systems show great ...
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2019
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Seeing the world’s smallest universal joints
Researchers at Osaka University used electron cryomicroscopy to produce the most accurate images to date of the bacterial flagellar hook. This work may help ...
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2019