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Dual control: plant peptide hormone generates distinct cell structures for water flow
An international collaboration including Osaka University researchers has found that a peptide hormone regulates two different cell division processes that ...
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2018
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Reading the Signs: Semaphorin Linked to Lung Cancer Treatment Resistance
Osaka University researchers showed that high levels of the protein Semaphorin 7a are associated with resistance to treatment with EGFR-TKIs in lung ...
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2018
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Non-invasive microscopy detects activation state and distinguishes between cell types
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2019
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Resist! TAK1 enables endothelial cells to avoid apoptosis
TNFα-induced cell death is tightly regulated and resisted in endothelial cells. Here, an Osaka University-led research team used a unique type of mouse, in ...
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2019
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Keeping Chromosomes in Check: A New Role for Heterochromatin
Large changes in the structure of chromosomes are usually fatal for the cell or can lead to genetic diseases such as cancer. Many large chromosomal ...
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2019
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Small Metabolites Have Big Effects on the Intestinal Immune Response
Normal gut bacteria are instrumental in inducing an immune response in the presence of invading pathogens. However, exactly how commensal bacteria cause ...
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2019
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More Physical Than Chemical: Researchers Show What Really Gets Cells Going
Collective cell migration is essential in many organisms, with roles in human cellular processes including cancer invasion and wound healing. Now, a team led ...
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2019
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When Good Cells Go Bad: Regulating the MS-Causing Properties of Th17 Cells
Multiple sclerosis (MS) and other inflammatory autoimmune diseases are characterized by localized inflammation in various tissues, including the brain. Using a ...
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2019
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The key to increased lifespan? Rubicon alters autophagy in animals during aging
Autophagy is an important biological recycling mechanism that influences the progression of aging in animals. Here, age-related changes in autophagy were ...
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2019
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Treatment to a T? Taking a BiTE Out of Lung Cancer
An Osaka University-led research team assayed T cell cytotoxicity in tumor tissue in lung cancer, along with normal lung tissue and peripheral blood. They ...
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2019