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Parkinson’s disease (PD) is a common neurodegenerative disorder, in which 15% of cases are linked to genetic mutations. The DNAJC13 gene has been linked to a ...

Osaka University researchers revealed that two molecules, PTEN and PIP3, mutually inhibit each other to ensure their exclusive distribution at opposite ends of ...

Collective cell migration is essential in many organisms, with roles in human cellular processes including cancer invasion and wound healing. Now, a team led ...

Gene therapy can potentially correct genetic disorders by directly editing defective genes. CRISPR-Cas9 is a popular gene-editing technology whose clinical ...

Osaka University researchers developed a novel method of identifying disease-related molecules and processes. They achieved this by integrating genetic data ...

Hematopoietic stem cells (HSCs) require specialized niches in bone marrow to generate functional blood cells. CAR cells are among cell types located in niches, ...

In eukaryotic cells, molecules can only move into or out of the nucleus through specialized channels called nuclear pore complexes (NPCs). Each NPC has a ring ...

Researchers at Osaka University used live imaging of the Drosophila embryonic hindgut and computer simulations to clarify that a novel cellular behavior called ...