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DNA repair supports brain cognitive development
Researchers at Osaka University showed that the enzyme Polβ functions in genome maintenance by preventing double-stranded breaks in DNA during brain ...
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2020
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Dual control: plant peptide hormone generates distinct cell structures for water flow
An international collaboration including Osaka University researchers has found that a peptide hormone regulates two different cell division processes that ...
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2018
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Efficacy of antibody targeting Devic’s disease proven in new animal model
Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG). A cure for NMO remains elusive. Osaka University ...
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2018
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Electron Accelerators Reveal the Radical Secrets of Antioxidants
An Osaka University professor has demonstrated for the first time the value of linear particle accelerators for the generation of free radicals inside ...
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2019
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Elucidation of 3D Structure of Protein That Can Eliminate Alzheimer’s Disease-Causing Agent
SorLA/LR11 is a unique neuronal sorting receptor considered to be a major genetic risk factor for Alzheimer’s disease. We have recently reported that it ...
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2015
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Embryonic microRNA-369 controls metabolic splicing factors and urges cellular reprogramming
A research team found a unique role of the embryonic miR-369-HNRNPA2B1 axis in controlling metabolic enzyme function. The data suggests a novel pathway linking ...
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2015
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Enzyme’s Unfrozen Adventure: In crystallo protein thermodynamics
Osaka University researchers and collaborators have reported the first in crystallo thermodynamic analysis of copper amine oxidase catalysis using a ...
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2018
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Eye-Opening Study Differentiates iPS Cells into Various Ocular Lineages
Osaka University researchers revealed that culturing human induced pluripotent stem cells with different isoforms of the extracellular component laminin led to ...
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2018
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Faulty DNA repair depresses neural development
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2017
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Faulty transportation of messenger RNA is the culprit in ALS
A team including Osaka University researchers has discovered a function for the protein missing in many types of ALS and FTLD, two neurodegenerative diseases. ...
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2020