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Clarifying the interplay between bone cells in bone remodeling
Bone homeostasis is regulated by communication between bone-forming mature osteoblasts (mOB) and bone-resorptive mature osteoclasts (mOC). However, the ...
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2018
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Magnesium makes chromosomes
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2018
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New computational method reveals chemoresistance drug targets
The methylation of deoxycytosine to form 5-methylcytosine (5mC) is an important feature of cancer. Extensive DNA methylation and transcription analyses have ...
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2018
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New genome-editing method “cuts back” on unwanted genetic mutations
Gene therapy can potentially correct genetic disorders by directly editing defective genes. CRISPR-Cas9 is a popular gene-editing technology whose clinical ...
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2018
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Study reveals genetic basis of quantitative traits and diseases in Japanese
Osaka University-centered researchers presented one of the largest non-European genome-wide association study (GWAS) of quantitative biological traits to date, ...
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2018
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Researchers find adult endothelial stem cells that can make fully functional blood vessels
Stem cells are increasingly used to treat disorders caused by defective tissues. The repair of blood vessels by vascular endothelial stem cells (VESCs) is an ...
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2018
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Helpful B cells lend a hand to developing neurons
Neuron myelination is critical to early mental development, and defects in myelination have been linked to neurodevelopmental disorders. Researchers at Osaka ...
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2018
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Genome does not like to excessively change in male germ cells
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2018
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Cholesterol leash: key tethering protein found to transport cellular cholesterol
Cholesterol is an essential component of living organisms, but the mechanisms that transport cholesterol inside the cell are poorly understood. Researchers at ...
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2018
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Formidable duo: protective effect of CD9 and CD81 in COPD and accelerated aging
Chronic obstructive pulmonary disease (COPD) is a disease of accelerated lung aging, but the mechanism remains unclear. Osaka University-centered researchers ...
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2018
