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The making of memory B cells and long-term immune responses
Researchers at Osaka University in Japan have identified two factors necessary for the production of memory B cells, the cells of the immune system that allow ...
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2020
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The making of mysterious mazes: how animals got their complex colorations
A researcher at Osaka University uncovered a simple mechanism underlying the intricate skin patterns of animals through comprehensive analyses of the diversity ...
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2020
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The Mincle receptor provides protective immunity against Group A Streptococcus
Group A Streptococcus (GAS) causes invasive infections that result in high mortality. Despite being susceptible to many antibiotics, GAS continues to cause ...
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2018
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The molecular underpinnings of immune cell migration
Researchers from Osaka University discovered a novel molecular mechanism by which immune cells migrate and reach sites of infection. By studying dendritic ...
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2021
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The mystery of masculinization in Daphnia magna unraveled
Researchers at Osaka University discovered lncRNAs to activate the male-determining gene doublesex1 (Dsx1) necessary for sex determination in the crustacean ...
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2018
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The path(way) less traveled in DNA double-strand break repair
Researchers from Osaka University have found that protein phosphatase 1 binds to RIF1 at double-strand DNA breaks to promote repair by the non-homologous end ...
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2021
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The protein that stands between us and autoimmunity
Researchers from Osaka University identified the epigenetic proteins Tet2 and Tet3 as key regulators of B cell function. They showed that these proteins ...
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2020
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The secret adaptive power of photosynthetic complex I is finally revealed
An international team including researchers from Osaka University has solved the structure of photosynthetic complex I using cryo-electron microscopy. Using ...
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2018
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Therapeutic and Diagnostic Functions of One Antibody for Pancreatic Cancer
Osaka University researchers developed monoclonal antibodies against CKAP4—a plasma membrane protein—and found that it was released from pancreatic cancer ...
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2019
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Tiny DNA Reader to Advance Development of Anticancer Drugs
Researchers at Osaka University have developed a novel method to determine exactly where anticancer drug molecules are incorporated into microscopic strands of ...
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2019