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Genomic cut and paste using a Class 1 CRISPR system
Repairing faulty genes to prevent and cure disease is something researchers have been working towards for many years. While Class 2 CRISPR systems show great ...
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2019
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Seeing the world’s smallest universal joints
Researchers at Osaka University used electron cryomicroscopy to produce the most accurate images to date of the bacterial flagellar hook. This work may help ...
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2019
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Protein defect leaves sperm chasing their tails
A team led by researchers from Osaka University have characterized a protein, called VSP, that keeps sperm swimming in straight lines. Deletion of the protein ...
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2019
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Hematopoietic stem cell marker: A key player in the ontogeny of hematopoiesis
A research team led by Osaka University revealed that Endothelial cell-selective adhesion molecule, a surface marker for hematopoietic stem cells and vascular ...
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2019
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Getting to the "Heart" of Heart Beats: Cardiac thin filament structure and function revealed
Osaka University team uses advanced electron cryomicroscopy and image analysis to reveal the structure of vital muscle thin filaments in the heart with the ...
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2020
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Key to beating colorectal cancer hiding in plain sight?
Colorectal cancer, one of the most common cancers in the developed world, is intrinsically resistant to many drug therapies. In an attempt to identify novel ...
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2020
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A new approach to calm that angry nose
Eosinophilic chronic rhinosinusitis (ECRS) is a type of airway disease that involves nasal inflammation. Here, semaphorin protein was found to contribute to ...
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2020
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A tadpole with a twist: Left–right asymmetric development of Oikopleura dioica
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2020
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How tissues harm themselves during wound healing
Researchers from Osaka University discovered that increased expression of Rbm7 in apoptotic tissue cells results in the recruitment of ...
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2020
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Modeling the human eye in a dish
Researchers from Osaka University developed and validated a novel PITX2-eGFP hiPSC reporter line to model the development of periocular mesenchymal cells. ...
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2020