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New computational method reveals chemoresistance drug targets
The methylation of deoxycytosine to form 5-methylcytosine (5mC) is an important feature of cancer. Extensive DNA methylation and transcription analyses have ...
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2018
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Study reveals genetic basis of quantitative traits and diseases in Japanese
Osaka University-centered researchers presented one of the largest non-European genome-wide association study (GWAS) of quantitative biological traits to date, ...
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2018
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Genome does not like to excessively change in male germ cells
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2018
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Dual control: plant peptide hormone generates distinct cell structures for water flow
An international collaboration including Osaka University researchers has found that a peptide hormone regulates two different cell division processes that ...
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2018
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Tiny DNA Reader to Advance Development of Anticancer Drugs
Researchers at Osaka University have developed a novel method to determine exactly where anticancer drug molecules are incorporated into microscopic strands of ...
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2019
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Helping select the cells with the most potential
Little is known about the mechanisms by which mammalian cells grow and differentiate during the handful of days between fertilization of the egg and ...
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2019
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A tadpole with a twist: Left–right asymmetric development of Oikopleura dioica
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2020
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Novel switch protein that ‘turns on’ sperm for fertilization
Researchers from Osaka University and Baylor College of Medicine discovered a signaling cascade in which the testicular protein NELL2 travels through the lumen ...
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2020
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DNA repair supports brain cognitive development
Researchers at Osaka University showed that the enzyme Polβ functions in genome maintenance by preventing double-stranded breaks in DNA during brain ...
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2020
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Meet the Smurfs: A bone metabolism family
Researchers from Osaka University and Ehime University have found that protein Smurf2 can regulate a cellular pathway that affects bone metabolism. Smurf2 can ...
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2020
