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Culprit in reducing effectiveness of insulin identified
Scientists at Osaka University discovered that Stromal derived factor-1 (SDF-1) secreted from adipocytes reduced the effectiveness of insulin in adipocytes and ...
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2018
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Getting things under control: new mouse model aids study of immunomodulation
Mice are resistant to immunomodulatory drugs (IMiDs). As a result, studying the effects of IMiDs was not possible in existing types of mice. Here, an Osaka ...
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2018
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Large-scale Study Reveals Genetic Risk of Diabetes in the Japanese Population
Researchers at Osaka University, The University of Tokyo, RIKEN, and others performed a meta-analysis using data on over 36,000 Japanese sufferers of type 2 ...
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2019
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Adipocyte glucocorticoid receptors play a role in developing steroid diabetes
Researchers at Osaka University focused on glucocorticoid receptors (GRs), the receptors for the body’s endogenous steroids, clarifying part of the mechanism ...
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2019
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Unforeseen links to chronic pancreatitis found in cancer-related signals
Researchers from Osaka University have demonstrated that two signaling pathways, the PI3K and the Hippo pathways earlier implicated in the development of ...
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2021
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Link discovered between male infertility and self-eating
Sertoli cells are important for spermatogenesis. Researchers at Osaka University have uncovered a novel regulatory mechanism of Sertoli cell function. ...
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2021
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Balancing between build-up and break-down of bone
Researchers at Osaka University have shown that SLPI, a secretory leukocyte protease inhibitor, coordinates the mutually contradictory actions of parathyroid ...
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2021
